News and Research

Radiation-induced vertebral compression fracture following spine stereotactic radiosurgery

Spine stereotactic radiosurgery (SRS) is increasingly being used to treat metastatic spinal tumors. As the experience matures, high rates of vertebral  compression fracture (VCF) are being observed. 
What is unknown is the mechanism of action; it has been postulated but not confirmed that radiation itself is a contributing factor. This case report describes 2 patients who were treated with spine SRS who subsequently developed signal changes on MRI consistent with tumor progression and VCF.

 

Percutaneous spine stabilisation prior to stereotactic radiosurgery for high risk spinal metastases

New, or progression of existing, vertebral compression fracture (VCF) post spine- stereotactic radiosurgery (SRS) for spinal metastases has been reported in the range of 10-39%. Lesion location, radiological appearance, presence of deformity, mechanical pain and percent of vertebral body involvement has reported as potential predictors of VCF. We report our pilot experience and retrospective analysis of patients thought to be at high risk of progressive VCF who were stabilized prophylactically with a percutaneous technique followed by spine SRS.